Dr. Paul De Sousa has trained as a developmental and reproductive biologist, with a specific interest in mechanisms controlling the creation of developmentally competent eggs and embryos. This training included graduate and post-doctoral research at the Universities of Toronto and Western Ontario in Canada, and University of Pennsylvania, in the USA.
In 1998 he joined the Roslin Institute in Scotland where he began applying his basic research interests to animal biotechnology, specifically the use of animal cloning by somatic cell nuclear transfer to create transgenic animals as models of disease and as organ donors for xenotransplantation. In 2002 his group began focusing on the derivation of new human embryo stem cells in accordance with emerging regulatory standards for therapeutic use.
In 2005 he joined the University of Edinburgh as a Senior Research Fellow and Project Manager developing both basic and applied research projects in developmental and stem cell biology.